Hasil Pencarian (2)
small molecule | CAS: 1668-19-5
Doxepin is a psychotropic agent with antidepressant and anxiolytic properties.[T559] It is a tertiary amine that can be presented as (E) and (Z) stereoisomers with the (Z) stereoisomer corresponding to [cidoxepin]. Doxepin commonly produces a 5:1 (E):(Z) race…
Kategori:
Acid ReducersAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists
+55
Target Protein:
Histamine H1 receptorHistamine H2 receptorSodium-dependent noradrenaline transporter
+16
Gen Terkait:
CYP2D6
CYP2D6
CYP2D6
+5
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe mean apparent v…
KlirensThe mean total appa…
Genetik
8 Varian
small molecule | CAS: 739-71-9
Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Kategori:
Adrenergic AgentsAdrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-Antagonists
+44
Target Protein:
Sodium-dependent serotonin transporterSodium-dependent noradrenaline transporterSodium-dependent dopamine transporter
+15
Gen Terkait:
CYP2D6
CYP2D6
CYP2D6
+5
Waktu Paruh11-18 hrs
Vol. Distribusi-
Klirens-
Genetik
8 Varian