Hasil Pencarian (2)
small molecule | CAS: 410528-02-8
Fibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million individuals, is an exceptionally rare genetic disorder.[A244920] FOP is caused by a gain-of-function mutation in the ACVR1/ALK2 gene which results in progr…
Kategori:
BCRP/ABCG2 InhibitorsBenzene DerivativesBenzylidene Compounds
+17
Target Protein:
Retinoic acid receptor gamma
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe mean (SD) appar…
KlirensThe apparent total …
Genetik
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small molecule | CAS: 895542-09-3
Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019.[L9013] Retinoids are a class of medications structurally and functionally analogous to [vitamin A], though lat…
Kategori:
AlkenesAnti-Acne PreparationsAnti-Acne Preparations for Topical Use
+11
Target Protein:
Retinoic acid receptor gammaRetinoic acid receptor betaRetinoic acid receptor alpha
Waktu ParuhThe terminal half-l…
Vol. Distribusi-
Klirens-
Genetik
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