Hasil Pencarian (2)
small molecule | CAS: 497871-47-3
Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers, including mesothelioma,[A214325] chronic lymphocytic leukemia (CLL),[A214328] breast cancer,[A214322] and small-cell lung cancer (SCLC).[A214310] It i…
Kategori:
Alkylating DrugsAntineoplastic AgentsAntineoplastic and Immunomodulating Agents
+12
Target Protein:
DNA
Waktu ParuhThe terminal half-l…
Vol. DistribusiThe steady-state vo…
KlirensThe total plasma cl…
Genetik
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small molecule | CAS: 114899-77-3
Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate _Ecteinascidia turbinata_ and now produced synthetically. Trabectedin has a unique mechanism of action. It binds to the minor…
Kategori:
Agents Causing Muscle ToxicityAlkylating ActivityAlkylating Drugs
+24
Target Protein:
DNA
Waktu Paruh33-50 hours
Vol. Distribusi-
Klirens-
Genetik
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