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Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
0 (0%)
Referensi
3 (100.0%)

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Hasil Pencarian (3)

Atogepant Approved DB16098
small molecule | CAS: 1374248-81-3

Atogepant is an oral antagonist of calcitonin gene-related peptide (CGRP) receptors indicated for the prevention of episodic migraine headaches. It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021.[L38814] While…

Kategori:
AnalgesicsAntimigraine PreparationsBCRP/ABCG2 Substrates +14
Target Protein:
Calcitonin gene-related peptide type 1 receptor
Waktu ParuhThe elimination hal…
Vol. DistribusiThe mean apparent v…
KlirensThe mean apparent o…
Genetik -
Phentermine Approved DB00191
small molecule | CAS: 122-09-8

Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine.[A174370] Phe…

Kategori:
Adrenergic AgentsAgents producing tachycardiaAgents that produce hypertension +22
Target Protein:
Sodium-dependent noradrenaline transporterSodium-dependent serotonin transporterSodium-dependent dopamine transporter +3
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe reported volume…
KlirensThe reported cleara…
Genetik -
Topiramate Approved DB00273
small molecule | CAS: 97240-79-4

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extende…

Kategori:
Alimentary Tract and MetabolismAnti-Obesity AgentsAnticonvulsants +23
Target Protein:
Glutamate receptor ionotropic, kainate 1Gamma-aminobutyric acid receptor subunit alpha-1Voltage-gated sodium channel alpha subunit +7
Waktu ParuhThe elimination hal…
Vol. DistribusiThe mean apparent v…
KlirensThe mean oral plasm…
Genetik -