Hasil Filter

3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
2 (66.7%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Glipizide Approved DB01067
small molecule | CAS: 29094-61-9

Glipizide is an oral hypoglycemic agent in the second-generation sulfonylurea drug class that is used to control blood sugar levels in patients with type 2 diabetes mellitus. It was first introduced in 1984 [A179491] and is available in various countries incl…

Kategori:
Alimentary Tract and MetabolismBlood Glucose Lowering AgentsBSEP/ABCB11 Substrates +11
Target Protein:
ATP-binding cassette sub-family C member 8ATP-sensitive inward rectifier potassium channel 10Peroxisome proliferator-activated receptor gamma
Gen Terkait:
CYP2C9
Waktu ParuhThe mean terminal e…
Vol. DistribusiThe mean volume of …
KlirensThe mean total body…
Genetik 1 Varian
small molecule | CAS: 70-55-3

Deskripsi belum tersedia.

Kategori:
AmidesBenzene DerivativesSulfonamides +2
Target Protein:
Carbonic anhydrase 2Carbonic anhydrase 12Carbonic anhydrase 6 +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tolbutamide Approved DB01124
small molecule | CAS: 64-77-7

Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues…

Kategori:
Alimentary Tract and MetabolismAmidesBenzene Derivatives +25
Target Protein:
ATP-binding cassette sub-family C member 9ATP-binding cassette sub-family C member 8ATP-sensitive inward rectifier potassium channel 1
Gen Terkait:
CYP2C9
Waktu ParuhApproximately 7 hou…
Vol. Distribusi-
Klirens-
Genetik 1 Varian