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Hasil Pencarian (2)

Mosunetuzumab Approved DB15434
biotech | CAS: 1905409-39-3

Mosunetuzumab is a humanized anti-CD20/CD3 bispecific antibody.[L42230] It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells.[A249320] The …

Kategori:
Amino Acids, Peptides, and ProteinsAntibodies, MonoclonalAntibodies, Monoclonal, Humanized +13
Target Protein:
B-lymphocyte antigen CD20T-cell surface glycoprotein CD3 epsilon chain
Waktu ParuhMosunetuzumab has a…
Vol. DistribusiThe estimated centr…
KlirensThe mean steady-sta…
Genetik -
Tisagenlecleucel Approved DB13881
biotech | CAS: 1823078-37-0

Tisagenlecleucel is a CD19-directed genetically modified autologous T cell immunotherapy, or a CAR-T cell therapy for B-cell acute lymphoblastic leukemia. It was granted approval by FDA in August 2017 under the market name Kymriah. Tisagenlecleucel is an immu…

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic AgentsAntineoplastic Agents, Immunological +10
Target Protein:
B-lymphocyte antigen CD19
Waktu ParuhThe mean half life …
Vol. DistribusiThe drug is found t…
Klirens-
Genetik -