Hasil Pencarian (2)
small molecule | CAS: 83799-24-0
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms.[L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain bar…
Kategori:
Anti-Allergic AgentsAntihistamines for Systemic UseBenzene Derivatives
+12
Target Protein:
Histamine H1 receptor
Waktu ParuhThe terminal elimin…
Vol. DistribusiThe volume of distr…
KlirensThe oral clearance …
Genetik
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small molecule | CAS: 50679-08-8
In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Kategori:
Anticholinergic AgentsAntihistamines for Systemic UseBenzene Derivatives
+31
Target Protein:
Histamine H1 receptorMuscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M1
+4
Waktu Paruh3.5 hours
Vol. Distribusi-
Klirens-
Genetik
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