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9

Total database: 17430
Struktur (SMILES)
9 (100.0%)
Target
6 (66.7%)
Genomik
0 (0%)
Referensi
9 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (9)

Acamprosate Approved DB00659
small molecule | CAS: 77337-76-9

Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending.[A229073] Acamprosate…

Kategori:
Alcohol DeterrentsCentral Nervous System AgentsDrugs Used in Addictive Disorders +8
Target Protein:
Glutamate (NMDA) receptorMetabotropic glutamate receptor 5Gamma-aminobutyric acid type B receptor subunit 1
Waktu ParuhIn pharmacokinetic …
Vol. DistribusiAt steady state con…
KlirensSevere renal insuff…
Genetik -
Cholic Acid Approved DB02659
small molecule | CAS: 81-25-4

A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Adm…

Kategori:
Alimentary Tract and MetabolismBile Acid PreparationsBile acids and derivatives +17
Target Protein:
Phospholipase A2Ferrochelatase, mitochondrialLiver carboxylesterase 1 +19
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
N-chlorotaurine DB06633
small molecule | CAS: 51036-13-6

N-chlorotaurine is an inhibitor of inducible nitric oxide synthase and IkappaB kinase.

Kategori:
AlkanesAlkanesulfonic AcidsAnti-Infective Agents +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 103-47-9

Deskripsi belum tersedia.

Kategori:
AlkanesAlkanesulfonic AcidsBuffers +4
Target Protein:
Sulfotransferase 2B1Nitrite reductaseHomeobox protein engrailed-2 +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Taurine Approved DB01956
small molecule | CAS: 107-35-7

Taurine, whose chemical name is 2-aminoethanesulfonic acid, is one of the most abundant amino acids in several organs. It plays important role in essential biological processes.[A31396] This conditional amino acid can be either be manufactured by the body or …

Kategori:
AlkanesAlkanesulfonic AcidsAmino Acids +5
Target Protein:
Glutamate receptor ionotropic, NMDA 2BGlycine receptor subunit betaGlycine receptor subunit alpha-2 +6
Waktu ParuhOral administration…
Vol. DistribusiThe distribution of…
KlirensThe clearance rate …
Genetik -
small molecule | CAS: 516-35-8

Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, …

Kategori:
AlkanesAlkanesulfonic AcidsBile Acids and Salts +18
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Taurocholic acid Approved DB04348
small molecule | CAS: 81-24-3

The product of conjugation of cholic acid with taurine. Its sodium salt is the chief ingredient of the bile of carnivorous animals. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and cholerectic.

Kategori:
AcidsAcids, NoncarboxylicAlkanes +30
Target Protein:
Ileal sodium/bile acid cotransporterG-protein coupled bile acid receptor 1Bile salt-activated lipase +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Taurolidine Approved DB12473
small molecule | CAS: 19388-87-5

Taurolidine is an antimicrobial used for the prevention of catheter-related infections. It is a derivative of the amino acid [taurine]. It was first synthesized in the 1970s and was originally used as a prophylactic against intraperitoneal bacterial infect…

Kategori:
AlkanesAlkanesulfonic AcidsAnti-Infective Agents +9
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Tauroursodeoxycholic acid Approved DB08834
small molecule | CAS: 14605-22-2

Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration.[A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therape…

Kategori:
Alimentary Tract and MetabolismBile acids and derivativesBile Acids and Salts +10
Target Protein:
Integrin alpha-5
Waktu Paruh-
Vol. DistribusiThere is evidence t…
Klirens-
Genetik -