Hasil Pencarian (2)
small molecule | CAS: 491833-29-5
Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid ?-glucosidase, an enzyme that converts glucosylcer…
Kategori:
Alimentary Tract and MetabolismCytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (strength unknown)
+15
Target Protein:
Ceramide glucosyltransferase
Waktu ParuhEliglustat has a te…
Vol. DistribusiIn CYP2D6 extensive…
KlirensIn healthy CYP2D6 e…
Genetik
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biotech | CAS: 37228-64-1
Taliglucerase alfa is the recombinant active form of the human lysosomal enzyme, ?-glucocerebrosidase. It was approved in 2012 and is marketed under the name Elelyso for use in patients with type 1 Gaucher's disease.
Kategori:
Alimentary Tract and MetabolismEnzyme Replacement TherapyEnzymes
+7
Target Protein:
Glucocerebroside
Waktu ParuhThe half life is be…
Vol. DistribusiThe steady state vo…
KlirensThe systemic cleara…
Genetik
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