Hasil Pencarian (2)
small molecule | CAS: 1802220-02-5
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene.[A262056] ROS1 mutations are one of the defin…
Kategori:
BCRP/ABCG2 InhibitorsCytochrome P-450 CYP2B6 InducersCytochrome P-450 CYP2B6 Inducers (strength unknown)
+28
Target Protein:
Proto-oncogene tyrosine-protein kinase ROSHigh affinity nerve growth factor receptorBDNF/NT-3 growth factors receptor
+1
Waktu ParuhThe repotrectinib m…
Vol. DistribusiThe geometric mean …
KlirensThe geometric mean …
Genetik
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