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7

Total database: 17430
Struktur (SMILES)
7 (100.0%)
Target
6 (85.7%)
Genomik
0 (0%)
Referensi
7 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (7)

Coblopasvir DB15315
small molecule | CAS: 1312608-46-0

Coblopasvir is under investigation in clinical trial NCT03416491 (Safety and Efficacy of KW-136 and Sofosbuvir for Treatment of Chronic Hepatitis C).

Kategori:
Antiinfectives for Systemic UseAntiviral AgentsAntivirals for Systemic Use +2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ledipasvir Approved DB09027
small molecule | CAS: 1256388-51-8

Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized int…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +10
Target Protein:
Genome polyproteinNonstructural protein 5A
Waktu ParuhThe median terminal…
Vol. Distribusi-
Klirens-
Genetik -
Ravidasvir DB15652
small molecule | CAS: 1242087-93-9

Ravidasvir is under investigation in clinical trial NCT02961426 (Sofosbuvir Plus Ravidasvir for the Treatment of HCV Chronic Infection).

Kategori:
Amino AcidsAmino Acids, Branched-ChainAmino Acids, Peptides, and Proteins +6
Target Protein:
Genome polyprotein
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Simeprevir Approved DB06290
small molecule | CAS: 923604-59-5

Simeprevir is a hepatitis C virus (HCV) NS3/4A protease inhibitor indicated in patient's with HCV genotype 1 for the treatment of chronic hepatitis C virus (HCV) infection. HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, w…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +37
Target Protein:
Genome polyproteinNS3 proteaseGenome polyprotein
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of si…
Genetik -
Sofosbuvir Approved DB08934
small molecule | CAS: 1190307-88-0

Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is c…

Kategori:
Anti-Infective AgentsAntiinfectives for Systemic UseAntiviral Agents +18
Target Protein:
Genome polyproteinRNA-dependent RNA-polymerase
Waktu ParuhSofosbuvir has a te…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of so…
Genetik -
Velpatasvir Approved DB11613
small molecule | CAS: 1377049-84-7

Velpatasvir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized in…

Kategori:
Acids, AcyclicAnti-Infective AgentsAntiinfectives for Systemic Use +22
Target Protein:
Nonstructural protein 5A
Waktu Paruh15h [FDA Label].
Vol. Distribusi1.4-1.6 L/kg [A191…
KlirensEstimated 0.12 L/h/…
Genetik -
Voxilaprevir Approved DB12026
small molecule | CAS: 1535212-07-7

Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized i…

Kategori:
Acids, AcyclicAmidesAmino Acids +36
Target Protein:
Genome polyproteinGenome polyprotein
Waktu Paruh33 hr [FDA Label]
Vol. Distribusi-
Klirens-
Genetik -