Hasil Filter

3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
1 (33.3%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

small molecule | CAS: 87857-41-8

Desmethylsertraline is a metabolite of sertraline.

Kategori:
Agents that reduce seizure thresholdAminesNaphthalenes +1
Target Protein:
ATP-dependent translocase ABCB1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Maralixibat Approved DB16226
small molecule | CAS: 716313-53-0

Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like [odevixibat].[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome.[L38834] …

Kategori:
Alimentary Tract and MetabolismBile and Liver TherapyBile Therapy +9
Target Protein:
Ileal sodium/bile acid cotransporterHepatic sodium/bile acid cotransporter
Waktu ParuhThe mean half life …
Vol. Distribusi-
Klirens-
Genetik -
Sertraline Approved DB01104
small molecule | CAS: 79617-96-2

Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor (SSRI), and is similar to drugs such as [Citalopram] and [Fluoxetine]. Despite marked structural differences between compounds in this drug class, SSR…

Kategori:
Agents that reduce seizure thresholdAminesAntidepressive Agents +39
Target Protein:
Sodium-dependent serotonin transporterSodium-dependent dopamine transporterSigma receptor +2
Gen Terkait:
CYP2C19 CYP2C19
Waktu ParuhThe elimination hal…
Vol. DistribusiSertraline is widel…
KlirensIn pharmacokinetic …
Genetik 2 Varian