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Total database: 17430
Struktur (SMILES)
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Target
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Genomik
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Hasil Pencarian (2)

Lopinavir Approved DB01601
small molecule | CAS: 192725-17-0

Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection.[L11163] Lopinavir is marketed and administered exclusively in combination with [ritonavir] - this combination, first marketed…

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +42
Target Protein:
Pol polyprotein
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe estimated appar…
Genetik -
Saquinavir Approved DB01232
small molecule | CAS: 127779-20-8

Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection. In 1995 it became the first protease inhibitor approved by the FDA, followed shortl…

Kategori:
Agents Causing Muscle ToxicityAnti-HIV AgentsAnti-Infective Agents +44
Target Protein:
Gag-Pol polyproteinPol polyprotein
Waktu Paruh-
Vol. DistribusiThe steady-state vo…
KlirensThe systemic cleara…
Genetik -