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Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
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Referensi
3 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (3)

Paliperidone Approved DB01267
small molecule | CAS: 144598-75-4

Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a com…

Kategori:
Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +37
Target Protein:
5-hydroxytryptamine receptor 2AD(2) dopamine receptorD(4) dopamine receptor +12
Waktu ParuhThe terminal elimin…
Vol. Distribusi* 487 L
Klirens-
Genetik -
Pipamperone DB09286
small molecule | CAS: 1893-33-0

Pipamperone is a typical antipsychotic of the _butyrophenone_ family used in the treatment of schizophrenia. It was developed by Janssen Pharmaceutica in 1961 and started its first round of clinical trials in 1963 [L1514, L1518]. In an effort to improve [h…

Kategori:
Antidepressive AgentsAntipsychotic AgentsButyrophenone Derivatives +15
Target Protein:
D(2) dopamine receptor5-hydroxytryptamine receptor 2AAlpha-1 adrenergic receptors +5
Waktu Paruh17-26h [L1522]
Vol. Distribusi-
Klirens-
Genetik -
Risperidone Approved DB00734
small molecule | CAS: 106266-06-2

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder.[L12885] It is one of the most widely used SGAs. [Paliperidone], another comm…

Kategori:
Adrenergic alpha-1 Receptor AntagonistsAdrenergic alpha-AntagonistsAdrenergic Antagonists +42
Target Protein:
5-hydroxytryptamine receptor 2AD(2) dopamine receptorAlpha-1B adrenergic receptor +9
Waktu Paruh3 hours in extensiv…
Vol. DistribusiThe volume of distr…
KlirensRisperidone is clea…
Genetik -