Hasil Pencarian (2)
small molecule | CAS: 1703793-34-3
Avapritinib, or BLU-285,[A189327] is a selective tyrosine kinase inhibitor of KIT and platelet derived growth factor receptor alpha indicated for the treatment of unresectable, metastatic gastrointestinal stromal tumors and advanced systemic mastocytosis.[A18…
Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Inhibitors
+17
Target Protein:
Platelet-derived growth factor receptor alphaMast/stem cell growth factor receptor Kit
Waktu ParuhThe half life of av…
Vol. DistribusiThe mean apparent v…
KlirensThe mean apparent o…
Genetik
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small molecule | CAS: 1442472-39-0
Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST) that has not adequately responded to other kinase inhibitors such as [sunitinib] and [imatinib]. Ripretinib, also known as Qinlock, is manufactured by De…
Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents
+19
Target Protein:
Mast/stem cell growth factor receptor KitPlatelet-derived growth factor receptor betaAngiopoietin-1 receptor
+3
Waktu ParuhThe average half-li…
Vol. DistribusiThe mean volume of …
KlirensThe mean apparent c…
Genetik
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