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3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
2 (66.7%)
Genomik
0 (0%)
Referensi
3 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

small molecule | CAS: 91503-79-6

Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).

Kategori:
Acids, AcyclicAnalgesicsAnalgesics, Non-Narcotic +8
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Remifentanil Approved DB00899
small molecule | CAS: 132875-61-7

Remifentanil (marketed by Abbott as Ultiva) is a potent ultra short-acting synthetic opioid given to patients during surgery for pain relief and adjunctive to an anaesthetic. Remifentanil is a specific mu-type-opioid receptor agonist which means it reduces sy…

Kategori:
Acids, AcyclicAgents producing tachycardiaAgents that produce hypertension +24
Target Protein:
Mu-type opioid receptorDelta-type opioid receptorKappa-type opioid receptor
Waktu Paruh1-20 minutes
Vol. Distribusi* 350 mL/kg * 452 …
Klirens* 40 mL/min/kg [you…
Genetik -
Remimazolam Approved DB12404
small molecule | CAS: 308242-62-8

Remimazolam is an ultra short-acting benzodiazepine used in the induction and maintenance of sedation during short (<30 minute) procedures.[L14647] Recent trends in anesthesia-related drug development have touted the benefits of so-called "soft drugs" - these…

Kategori:
BenzazepinesBenzodiazepine hypnotics and sedativesBenzodiazepines and benzodiazepine derivatives +8
Target Protein:
Gamma-aminobutyric acid receptor subunit gamma-3GABA(A) ReceptorGABA(A) Receptor Benzodiazepine Binding Site
Waktu ParuhFollowing intraveno…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of re…
Genetik -