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Total database: 17430
Struktur (SMILES)
2 (100.0%)
Target
2 (100.0%)
Genomik
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Referensi
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Hasil Pencarian (2)

Linzagolix Approved DB17083
small molecule | CAS: 935283-04-8

Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other…

Kategori:
Anti-Gonadotropin-Releasing HormonesBCRP/ABCG2 SubstratesCytochrome P-450 CYP2C8 Inhibitors +18
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhThe half-life of li…
Vol. DistribusiAfter seven days of…
KlirensThe geometric mean …
Genetik -
Relugolix Approved DB11853
small molecule | CAS: 737789-87-6

Relugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions. It was first approved in Japan in 2019, under the brand name Relumina, for the symptomatic treatment of uterine fibroids,[…

Kategori:
AmidesAnti-Gonadotropin-Releasing HormonesAntiandrogens +30
Target Protein:
Gonadotropin-releasing hormone receptor
Waktu ParuhThe average effecti…
Vol. Distribusi-
KlirensThe average renal c…
Genetik -