Hasil Pencarian (2)
biotech | CAS: 946414-94-4
Nivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1).[L12129] This antibody was produced entirely in mice and grafted onto human kappa and IgG4 Fc region with the mutation _S228P_ for additional stability…
Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntibodies
+20
Target Protein:
Programmed cell death protein 1Programmed cell death 1 ligand 1
Waktu ParuhThe serum half life…
Vol. DistribusiThe volume of distr…
KlirensThe estimated clear…
Genetik
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biotech | CAS: 1673516-98-7
Relatlimab is a human IgG4 monoclonal antibody and novel immune checkpoint inhibitor that targets lymphocyte activation gene-3 (LAG-3).[A246165,L41265] It was the first commercially developed anti-LAG-3 antibody, entering clinical trials in 2013,[A246155] and…
Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal
+12
Target Protein:
Lymphocyte activation gene 3 protein
Waktu ParuhThe geometric mean …
Vol. DistribusiThe geometric mean …
KlirensAt steady-state, th…
Genetik
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