Hasil Pencarian (2)
small molecule | CAS: 1194506-26-7
Fruquintinib is a novel small-molecule anti-VEGFR that targets VEGFR-1,-2, and -3 to inhibit angiogenesis. Tumor angiogenesis is one of the most critical biological processes for increasing oxygen and nutrient supply to cancer cells, and the VEGF/VEGFR pathwa…
Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsCytochrome P-450 CYP2C19 Substrates
+10
Target Protein:
Vascular endothelial growth factor receptor 1Vascular endothelial growth factor receptor 2Vascular endothelial growth factor receptor 3
Waktu ParuhThe fruquintinib's …
Vol. DistribusiThe mean (SD) appar…
KlirensThe apparent cleara…
Genetik
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small molecule | CAS: 755037-03-7
Regorafenib is an orally-administered inhibitor of multiple kinases. It is used for the treatment of metastatic colorectal cancer, advanced gastrointestinal stromal tumours, and hepatocellular carcinoma. FDA approved on September 27, 2012. Approved use of Reg…
Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents
+31
Target Protein:
Vascular endothelial growth factor receptor 1Vascular endothelial growth factor receptor 2Vascular endothelial growth factor receptor 3
+15
Waktu ParuhRegorafenib, 160 mg…
Vol. DistribusiRegorafenib undergo…
Klirens-
Genetik
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