Hasil Pencarian (2)
small molecule | CAS: 1903768-17-1
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematologic disease characterized by hemolysis, thrombophilia, and bone marrow dysfunction.[A263501,L50417] Both hemolysis and thrombophilia are mediated primarily by the complement system.[A263501]…
Kategori:
AminesAmino AcidsAmino Acids, Cyclic
+10
Target Protein:
Complement factor D
Waktu ParuhThe mean half-life …
Vol. DistribusiThe apparent volume…
KlirensThe mean apparent c…
Genetik
-
biotech | CAS: 1803171-55-2
Ravulizumab is a potent and selective complement 5 (C5) inhibitor. It is a humanized monoclonal IgG2/4 kappa antibody produced in Chinese hamster ovary (CHO) cells.[L39690] Ravulizumab was engineered from [eculizumab], another complement inhibitor, to increas…
Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal
+15
Target Protein:
Complement C5
Waktu ParuhThe mean (%CV) term…
Vol. DistribusiThe mean (%CV) volu…
KlirensThe mean (%CV) clea…
Genetik
-