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4

Total database: 17430
Struktur (SMILES)
4 (100.0%)
Target
3 (75.0%)
Genomik
0 (0%)
Referensi
4 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Acrivastine Approved DB09488
small molecule | CAS: 87848-99-5

Acrivastine is a triprolidine analog antihistamine indicated for the treatment of allergies and hay fever. As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histami…

Kategori:
Antihistamines for Systemic UseDrugs that are Mainly Renally ExcretedHistamine Agents +7
Target Protein:
Histamine H1 receptor
Waktu ParuhThe mean terminal h…
Vol. Distribusi0.46 ± 0.05 L/kg
Klirens2.9 ± 0.7 mL/min/kg
Genetik -
Cathine DB01486
small molecule | CAS: 492-39-7

Cathine, also known as d-norpseudoephedrine and (+)-norpseudoephedrine, is a psychoactive drug with stimulant properties. It belongs to the phenethylamine and amphetamine chemical classes. In the United States, it is classified as a Schedule IV controlled sub…

Kategori:
AlcoholsAlimentary Tract and MetabolismAmines +7
Waktu Paruh5.2 +/- 3.4 hours
Vol. Distribusi-
Klirens-
Genetik -
Ephedrine Approved DB01364
small molecule | CAS: 299-42-3

Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].[A193698] Ephedrine acts as both a direct and indirect sympathomimetic. It is an alpha- and beta-adrenergic rece…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-Agonists +39
Target Protein:
D(2) dopamine receptorAlpha-1A adrenergic receptorBeta-1 adrenergic receptor +2
Waktu ParuhOral ephedrine has …
Vol. DistribusiOral ephedrine has …
KlirensOral ephedrine has …
Genetik -
Pseudoephedrine Approved DB00852
small molecule | CAS: 90-82-4

Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first res…

Kategori:
Adrenergic AgonistsAdrenergic alpha-1 Receptor AgonistsAdrenergic alpha-2 Receptor Agonists +30
Target Protein:
Sodium-dependent noradrenaline transporterD(2) dopamine receptorSodium-dependent dopamine transporter +10
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe apparent volume…
KlirensA 60mg oral dose of…
Genetik -