Hasil Pencarian (2)
small molecule | CAS: 60-56-0
Methimazole is a thionamide antithyroid agent that inhibits the synthesis of thyroid hormones.[A184559,A184733,A184694] It was first introduced as an antithyroid agent in 1949[A184502] and is now commonly used in the management of hyperthyroidism, particularl…
Kategori:
Antithyroid agentsCytochrome P-450 CYP1A2 InhibitorsCytochrome P-450 CYP1A2 Inhibitors (strength unknown)
+30
Target Protein:
Thyroid peroxidase
Waktu ParuhFollowing a single …
Vol. DistribusiThe apparent volume…
KlirensFollowing a single …
Genetik
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small molecule | CAS: 51-52-5
A thiourea antithyroid agent. Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism. (From Martindale, The Extra Pharmacopeoia, 30th ed, p534)
Kategori:
Agents Causing Muscle ToxicityAntimetabolitesAntithyroid agents
+14
Target Protein:
Type I iodothyronine deiodinaseThyroid peroxidase
Waktu Paruh2 hours
Vol. Distribusi-
Klirens-
Genetik
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