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Total database: 17430
Struktur (SMILES)
9 (100.0%)
Target
8 (88.9%)
Genomik
0 (0%)
Referensi
9 (100.0%)

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Hasil Pencarian (9)

Acecainide DB17602
small molecule | CAS: 32795-44-1

Acecainide is an investigational anti-arrhythmia drug.

Kategori:
Acids, CarbocyclicAminobenzoatesAntiarrhythmic agents +5
Target Protein:
Sodium channel protein type 5 subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Benzonatate Approved DB00868
small molecule | CAS: 104-31-4

Benzonatate is an oral antitussive drug used in the relief and suppression of cough in patients older than ten years of age.[A5790] Currently, benzonatate is the only non-narcotic antitussive available as a prescription drug.[A189519] It works to reduce the a…

Kategori:
AlkanesAminesAntitussive Agents +8
Target Protein:
Sodium channel protein type 5 subunit alpha
Waktu ParuhThe half life of be…
Vol. DistribusiThere is limited in…
KlirensThere is limited in…
Genetik -
Chloroprocaine Approved DB01161
small molecule | CAS: 133-16-4

Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride. Similar to other local anesthetics, it increases the threshold for electrical excitation in nerves by slowing the propagation of the nerve impulse a…

Kategori:
Acids, CarbocyclicAminobenzoatesAnesthetics +15
Target Protein:
Sodium/potassium-transporting ATPase subunit alpha-1Voltage-gated sodium channel alpha subunitSodium-dependent dopamine transporter
Waktu ParuhIn adults, the aver…
Vol. Distribusi-
Klirens-
Genetik -
Oxybuprocaine Approved DB00892
small molecule | CAS: 99-43-4

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ion…

Kategori:
Acids, CarbocyclicAminobenzoatesAnesthetics +15
Target Protein:
Sodium channel protein type 10 subunit alpha
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Procainamide Approved DB01035
small molecule | CAS: 51-06-9

A derivative of procaine with less CNS action.

Kategori:
Acids, CarbocyclicAgents Causing Muscle ToxicityAgents that produce neuromuscular block (indirect) +32
Target Protein:
Voltage-gated inwardly rectifying potassium channel KCNH2Sodium channel protein type 5 subunit alphaDNA (cytosine-5)-methyltransferase 1
Waktu Paruh~2.5-4.5 hours
Vol. Distribusi* 2 L/kg
Klirens-
Genetik -
Procaine Approved DB00721
small molecule | CAS: 59-46-1

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also b…

Kategori:
Acids, CarbocyclicAgents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAgents that reduce seizure threshold +25
Target Protein:
Sodium channel protein type 10 subunit alphaGlutamate receptor ionotropic, NMDA 3A5-hydroxytryptamine receptor 3A +8
Waktu Paruh7.7 minutes
Vol. Distribusi-
Klirens-
Genetik -
Procaine benzylpenicillin Approved DB09320
small molecule | CAS: 54-35-3

Procaine benzylpenicillin (INN), also known as procaine G penicillin, is an injectable antiobiotic. It is a poorly soluble salt form of penicillin which is a combination of naturally occuring benzylpenicillin (penicillin G) and the local anaesthetic agent pro…

Kategori:
Acids, CarbocyclicAmidesAminobenzoates +16
Target Protein:
Penicillin-binding protein
Waktu ParuhIntramuscular injec…
Vol. DistribusiThe drug is distrib…
Klirens-
Genetik -
Procaine merethoxylline Approved DB09364
small molecule | CAS: 60064-28-0

Deskripsi belum tersedia.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Propoxycaine Approved DB09342
small molecule | CAS: 86-43-1

Propoxycaine is a local anesthetic of the ester type that has a rapid onset of action and a longer duration of action than procaine hydrochloride [L1588]. This drug was removed from the US market in 1996. Although no longer available in the United States,…

Kategori:
Acids, CarbocyclicAminobenzoatesAnesthetics +11
Target Protein:
Voltage-gated sodium channel alpha subunit
Waktu Paruh-
Vol. Distribusi-
KlirensVia the kidneys, pr…
Genetik -