Hasil Pencarian (2)
small molecule | CAS: 380449-51-4
Melphalan flufenamide, also known as melflufen or J1, is a prodrug of [melphalan].[A230123,L32173] Melphalan flufenamide is more readily uptaken by cells than melphalan, and is cleaved to the active metabolite by aminopeptidases.[A230123] _In vitro_ models sh…
Kategori:
Alkylating ActivityAlkylating DrugsAmino Acids
+12
Target Protein:
DNA
Waktu ParuhThe mean eliminatio…
Vol. DistribusiThe mean volume of …
KlirensThe mean clearance …
Genetik
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small molecule | CAS: 19171-19-8
Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. FDA approved on February 8, 2013.
Kategori:
Acids, CarbocyclicAngiogenesis InhibitorsAngiogenesis Modulating Agents
+29
Target Protein:
Protein cereblonTumor necrosis factorProstaglandin G/H synthase 2
Waktu ParuhHealthy subjects = …
Vol. DistribusiMean apparent volum…
KlirensTotal body clearanc…
Genetik
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