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Total database: 17430
Struktur (SMILES)
4 (100.0%)
Target
4 (100.0%)
Genomik
0 (0%)
Referensi
4 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (4)

small molecule | CAS: 461-78-9

A sympathomimetic agent that was formerly used as an anorectic. It has properties similar to those of dextroamphetamine. It has been implicated in lipid storage disorders and pulmonary hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1223)

Kategori:
Agents producing tachycardiaAgents that produce hypertensionAmines +7
Target Protein:
Sodium-dependent serotonin transporter
Waktu Paruh40 hours
Vol. Distribusi-
Klirens-
Genetik -
Mephentermine Approved DB01365
small molecule | CAS: 100-92-5

A sympathomimetic agent with mainly indirect effects on adrenergic receptors. It is used to maintain blood pressure in hypotensive states, for example, following spinal anesthesia. Although the central stimulant effects of mephentermine are much less than tho…

Kategori:
Adrenergic AgentsAdrenergic AgonistsAdrenergic alpha-1 Receptor Agonists +17
Target Protein:
Alpha adrenergic receptorD(2) dopamine receptorBeta adrenergic receptor
Waktu Paruh17 to 18 hours.
Vol. Distribusi-
Klirens-
Genetik -
Phentermine Approved DB00191
small molecule | CAS: 122-09-8

Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine.[A174370] Phe…

Kategori:
Adrenergic AgentsAgents producing tachycardiaAgents that produce hypertension +22
Target Protein:
Sodium-dependent noradrenaline transporterSodium-dependent serotonin transporterSodium-dependent dopamine transporter +3
Waktu ParuhThe mean terminal h…
Vol. DistribusiThe reported volume…
KlirensThe reported cleara…
Genetik -
Topiramate Approved DB00273
small molecule | CAS: 97240-79-4

Topiramate is a anti-epileptic drug used to manage seizures and prevent migraines.[A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.[A188309,L10544,L43478] Since 2012, the extende…

Kategori:
Alimentary Tract and MetabolismAnti-Obesity AgentsAnticonvulsants +23
Target Protein:
Glutamate receptor ionotropic, kainate 1Gamma-aminobutyric acid receptor subunit alpha-1Voltage-gated sodium channel alpha subunit +7
Waktu ParuhThe elimination hal…
Vol. DistribusiThe mean apparent v…
KlirensThe mean oral plasm…
Genetik -