Hasil Pencarian (2)
small molecule | CAS: 872511-34-7
Infigratinib is a pan-fibroblast growth factor receptor (FGFR) kinase inhibitor. By inhibiting the FGFR pathway, which is often aberrated in cancers such as cholangiocarcinoma, infigratinib suppresses tumour growth.[A235174] Cholangiocarcinoma is the most com…
Kategori:
AmidesAntineoplastic AgentsAntineoplastic and Immunomodulating Agents
+24
Target Protein:
Fibroblast growth factor receptor 1Fibroblast growth factor receptor 2Fibroblast growth factor receptor 3
+1
Waktu ParuhThe geometric mean …
Vol. DistribusiAt steady state, th…
KlirensThe geometric mean …
Genetik
-
small molecule | CAS: 1513857-77-6
Pemigatinib is a small molecule kinase inhibitor with antitumour activity. It works by inhibiting fibroblast growth factor receptors (FGFRs), which are receptor tyrosine kinases that activate signalling pathways in tumour cells.[A193719] FGFRs gained attentio…
Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Substrates
+16
Target Protein:
Fibroblast growth factor receptor 1Fibroblast growth factor receptor 2Fibroblast growth factor receptor 3
+1
Waktu ParuhFollowing administr…
Vol. DistribusiThe apparent volume…
KlirensFollowing administr…
Genetik
-