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Total database: 17430
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10 (90.9%)
Target
6 (54.5%)
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11 (100.0%)

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Hasil Pencarian (11)

Alatrofloxacin Approved DB09335
small molecule | CAS: 146961-76-4

Alatrofloxacin is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. It was withdrawn from the U.S. market in 2001.

Kategori:
4-QuinolonesAnti-Infective AgentsEnzyme Inhibitors +6
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ciprofloxacin Approved DB00537
small molecule | CAS: 85721-33-1

Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics.[A178870] It is formulated for oral, intravenous, intratympanic, ophthalmic, and otic administration for a number of bacterial infections.[L6469,L6472,L6475,L647…

Kategori:
4-QuinolonesAgents Causing Muscle ToxicityAnti-Bacterial Agents +38
Target Protein:
DNA topoisomerase 4 subunit ADNA gyrase subunit BThymidylate synthase +10
Waktu ParuhThe average half li…
Vol. DistribusiCirpofloxacin follw…
KlirensThe average renal c…
Genetik -
D-Levofloxacin DB03034
small molecule | CAS: 100986-86-5

A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.

Target Protein:
Autolysin
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Danofloxacin DB11393
small molecule | CAS: 112398-08-0

Danofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.

Kategori:
4-QuinolonesAnti-Infective AgentsHeterocyclic Compounds, Fused-Ring +2
Target Protein:
DNA gyrase subunit ADNA gyrase subunit B
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Enrofloxacin DB11404
small molecule | CAS: 93106-60-6

Enrofloxacin is an antibiotic agent from the fluoroquinolone family produced by the Bayer Corporation. Enrofloxacin is approved by the FDA for its veterinary use. Due to the identification of fluoroquinolone-resistant strains of _Campylobacter_, in September …

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +7
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Levofloxacin Approved DB01137
small molecule | CAS: 100986-85-4

Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin].[A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin[A190663] and remains…

Kategori:
4-QuinolonesAlimentary Tract and MetabolismAnti-Bacterial Agents +35
Target Protein:
DNA gyrase subunit ADNA gyrase subunit BDNA gyrase subunit A +1
Waktu ParuhThe average termina…
Vol. DistribusiLevofloxacin is wid…
KlirensThe average apparen…
Genetik -
Marbofloxacin DB11426
small molecule | CAS: 115550-35-1

Marbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine. A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under the name Aurizon.

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ofloxacin Approved DB01165
small molecule | CAS: 82419-36-1

A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Kategori:
4-QuinolonesAgents Causing Muscle ToxicityAnti-Bacterial Agents +22
Target Protein:
DNA gyrase subunit ADNA gyrase subunit BDNA gyrase subunit A +2
Waktu Paruh9 hours
Vol. Distribusi-
Klirens-
Genetik -
Pradofloxacin DB11453
small molecule | CAS: 195532-12-8

Pradofloxacin is a 3rd generation fluoroquinolone antibiotic developed by Bayer HealthCare AG, Animal Health GmBH. It was approved by the European Commission in April 2011 for bacterial infections in dogs and cats.

Kategori:
4-QuinolonesAnti-Bacterial AgentsFluoroquinolone Antibacterial +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 374107-43-4

99mTc-Ciprofloxacin is a new formulation of ciprofloxacin (INFECTON), being investigated as a radioimaging agent for the potential diagnosis of infection, including fever of unknown origin, osteomyelitis, wound infection, abdominal abscess, pneumonia, appendi…

Kategori:
4-QuinolonesAnti-Bacterial AgentsCytochrome P-450 CYP1A2 Inhibitors +9
Target Protein:
DNA gyrase subunit BDNA topoisomerase 2-beta
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Zabofloxacin DB12479
small molecule | CAS: 219680-11-2

Zabofloxacin has been used in trials studying the treatment of Community Acquired Pneumonia and Chronic Obstructive Pulmonary Disease.

Kategori:
4-QuinolonesHeterocyclic Compounds, Fused-RingQuinolines +1
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -