Hasil Pencarian (2)
small molecule | CAS: 716313-53-0
Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like [odevixibat].[A236823,A239249,L38834] Maralixibat is indicated for the treatment of cholestatic pruritus in patients with Alagille syndrome.[L38834] …
Kategori:
Alimentary Tract and MetabolismBile and Liver TherapyBile Therapy
+9
Target Protein:
Ileal sodium/bile acid cotransporterHepatic sodium/bile acid cotransporter
Waktu ParuhThe mean half life …
Vol. Distribusi-
Klirens-
Genetik
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small molecule | CAS: 501692-44-0
Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC).[A236808,L34793] Odevixibat is the first approved non…
Kategori:
Acids, AcyclicAlimentary Tract and MetabolismBenzazepines
+9
Target Protein:
Ileal sodium/bile acid cotransporter
Waktu ParuhA 7.2 mg oral dose …
Vol. DistribusiThe majority of adu…
KlirensThe majority of adu…
Genetik
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