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4

Total database: 17430
Struktur (SMILES)
4 (100.0%)
Target
4 (100.0%)
Genomik
0 (0%)
Referensi
4 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Erythrityl tetranitrate Approved DB01613
small molecule | CAS: 7297-25-8

A vasodilator with general properties similar to nitroglycerin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1020)

Kategori:
AlcoholsAntianginal AgentsCarbohydrates +7
Target Protein:
Atrial natriuretic peptide receptor 1Atrial natriuretic peptide receptor 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Isosorbide dinitrate Approved DB00883
small molecule | CAS: 87-33-2

A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.

Kategori:
Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAlcoholsAntianginal Agents +17
Target Protein:
Atrial natriuretic peptide receptor 1
Waktu Paruh1 hour
Vol. Distribusi* 2 to 4 L/kg
Klirens-
Genetik -
Isosorbide mononitrate Approved DB01020
small molecule | CAS: 16051-77-7

Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.[L11698, L11743] Isosorbide mono…

Kategori:
AlcoholsAntianginal AgentsCarbohydrates +14
Target Protein:
Guanylate cyclase soluble subunit alpha-2
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe total body clea…
Genetik -
Nitroglycerin Approved DB00727
small molecule | CAS: 55-63-0

Nitroglycerin, also known as glyceryl trinitrate,[A180169] is an organic nitrate and a vasodilating agent [L38369] that was first discovered in 1847.[A249965] Originally used to dynamite, its antianginal effects were identified in the late 1860s after it prod…

Kategori:
Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAntianginal AgentsAntihypertensive Agents +14
Target Protein:
Epidermal growth factor receptorGuanylate cyclase soluble subunit alpha-1Guanylate cyclase soluble subunit beta-1 +1
Waktu ParuhFollowing intraveno…
Vol. DistribusiThe volume of distr…
KlirensThe estimated clear…
Genetik -