Hasil Pencarian (2)
small molecule | CAS: 2628280-40-8
Nirmatrelvir (PF-07321332) is an orally bioavailable 3C-like protease (3CL<sup>PRO</sup>) inhibitor that is the subject of clinical trial NCT04756531.[L33354] 3CL<sup>PRO</sup> is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2.[A234224] Withou…
Kategori:
AmidesAmino AcidsAmino Acids, Branched-Chain
+22
Target Protein:
Replicase polyprotein 1ab
Waktu ParuhThe mean half-life …
Vol. DistribusiThe mean volume of …
KlirensThe mean oral clear…
Genetik
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small molecule | CAS: 155213-67-5
Ritonavir is an HIV protease inhibitor that interferes with the reproductive cycle of HIV. Although it was initially developed as an independent antiviral agent, it has been shown to possess advantageous properties in combination regimens with low-dose ritona…
Kategori:
Acids, AcyclicAgents Causing Muscle ToxicityAnti-HIV Agents
+69
Target Protein:
Gag-Pol polyproteinPol polyproteinNuclear receptor subfamily 1 group I member 2
Waktu ParuhThe approximate hal…
Vol. DistribusiThe estimated volum…
KlirensThe apparent oral c…
Genetik
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