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29

Total database: 17430
Struktur (SMILES)
28 (96.6%)
Target
20 (69.0%)
Genomik
0 (0%)
Referensi
29 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (29)

small molecule

A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alter…

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +6
Target Protein:
4-hydroxy-tetrahydrodipicolinate reductase
Waktu Paruh-
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Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
NADPH-ferredoxin reductase FprA
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small molecule

Deskripsi belum tersedia.

Target Protein:
Alcohol dehydrogenase 1C
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Genetik -
small molecule | CAS: 28733-43-9

Deskripsi belum tersedia.

Target Protein:
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
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small molecule

Deskripsi belum tersedia.

Target Protein:
NAD(P) transhydrogenase, mitochondrial
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small molecule | CAS: 913556-61-3

Deskripsi belum tersedia.

Kategori:
Amino Acids, Peptides, and ProteinsOrganometallic CompoundsPeptides +1
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small molecule

Deskripsi belum tersedia.

Target Protein:
Poly [ADP-ribose] polymerase 1
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Ethionamide Approved DB00609
small molecule | CAS: 536-33-4

A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)

Kategori:
Anti-Bacterial AgentsAnti-Infective AgentsAntiinfectives for Systemic Use +9
Target Protein:
Enoyl-[acyl-carrier-protein] reductase [NADH]Nuclear factor erythroid 2-related factor 2Catalase-peroxidase
Waktu Paruh2 to 3 hours
Vol. Distribusi* 93.5 L [healthy v…
Klirens-
Genetik -
Inositol nicotinate Approved DB08949
small molecule | CAS: 6556-11-2

Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yi…

Kategori:
Cardiovascular AgentsNicotinic Acid and DerivativesOther Nutritional Agents +5
Target Protein:
Hydroxycarboxylic acid receptor 3Hydroxycarboxylic acid receptor 2
Waktu ParuhMean elimination ha…
Vol. DistribusiMean Vd following i…
KlirensMean clearance rate…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Vascular endothelial growth factor receptor 2
Waktu Paruh-
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small molecule | CAS: 114-33-0

N-methylnicotinamide is an experimental drug with no approved indication or marketed formulation. It is a metabolite of niacinamide/nicotinamide and niacin/nicotinic acid (vitamin B3), and as such N-methylnicotinamide is used to diagnose niacin deficiency by …

Kategori:
Alimentary Tract and MetabolismBile and Liver TherapyBile Therapy +7
Waktu Paruh-
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small molecule

Deskripsi belum tersedia.

Target Protein:
Serine/threonine-protein kinase Chk1
Waktu Paruh-
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NADH Approved DB00157
small molecule | CAS: 58-68-4

NADH is the reduced form of NAD+, and NAD+ is the oxidized form of NADH, a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic r…

Kategori:
Adenine NucleotidesCoenzymesDietary Supplements +8
Target Protein:
NADH-ubiquinone oxidoreductase chain 3UDP-glucose 6-dehydrogenaseAlcohol dehydrogenase 1A +141
Waktu Paruh-
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Nadide DB14128
small molecule | CAS: 53-84-9

A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately o…

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +6
Target Protein:
17-beta-hydroxysteroid dehydrogenase type 1Lysosomal alpha-glucosidaseNeutral alpha-glucosidase AB +8
Waktu Paruh-
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NADPH DB02338
small molecule | CAS: 53-57-6

Deskripsi belum tersedia.

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +6
Target Protein:
Thioredoxin reductase 1, cytoplasmicGlucose-6-phosphate 1-dehydrogenasePteridine reductase 1 +3
Waktu Paruh-
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Niacinamide ascorbate Approved DB14486
small molecule | CAS: 1987-71-9

Deskripsi belum tersedia.

Kategori:
Urinary Acidifying AgentsVitamin B ComplexVitamin C and analogues +1
Waktu Paruh-
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Nialamide Approved DB04820
small molecule | CAS: 51-12-7

Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.

Kategori:
Agents that produce hypertensionAgents that reduce seizure thresholdAntidepressive Agents +11
Target Protein:
Amine oxidase [flavin-containing] BAmine oxidase [flavin-containing] ACatechol O-methyltransferase
Waktu Paruh-
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Nicorandil Approved DB09220
small molecule | CAS: 65141-46-0

Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasod…

Kategori:
Agents causing hyperkalemiaAntiarrhythmic agentsAntihypertensive Agents +10
Target Protein:
ATP-binding cassette sub-family C member 9
Waktu ParuhThe elimination hal…
Vol. DistribusiAfter oral (and i.v…
KlirensThe total body clea…
Genetik -
Nicotinamide Approved DB02701
small molecule | CAS: 98-92-0

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency …

Kategori:
Alimentary Tract and MetabolismCytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (strength unknown) +13
Target Protein:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2Exotoxin APoly [ADP-ribose] polymerase 1 +2
Waktu Paruh-
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small molecule

Deskripsi belum tersedia.

Target Protein:
6-phosphogluconate dehydrogenase, decarboxylating
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small molecule

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small molecule

Deskripsi belum tersedia.

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small molecule | CAS: 53-59-8

Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of react…

Kategori:
Adenine NucleotidesCoenzymesEnzymes and Coenzymes +6
Target Protein:
Isocitrate dehydrogenase [NADP]Aldo-keto reductase family 1 member B1Glucose-6-phosphate 1-dehydrogenase +57
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small molecule

3-Carbamoyl-1-beta-D-ribofuranosyl pyridinium hydroxide-5'phosphate, inner salt. A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubC…

Kategori:
Nucleic Acids, Nucleotides, and NucleosidesNucleotidesRibonucleotides
Target Protein:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 +1
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small molecule | CAS: 1341-23-7

Nicotinamide riboside is under investigation in clinical trial NCT03432871 (Nicotinamide Riboside and Mitochondrial Biogenesis).

Kategori:
Nicotinic AcidsPyridines
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small molecule

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Omidubicel Approved DB17132
biotech

Omidubicel is a nicotinamide-modified allogeneic hematopoietic progenitor cell therapy derived from cord blood used as an allogeneic stem cell donor source. Umbilical blood cord cells are expanded _ex-vivo_ and [nicotinamide] (a form of vitamin B3) is used as…

Kategori:
Allogeneic Cord Blood Hematopoietic Progenitor Cell TherapyCells, AllogeneicCells, Cultured, Allogeneic +1
Waktu ParuhThere is limited ph…
Vol. DistribusiThere is limited ph…
KlirensThere is limited ph…
Genetik -
small molecule

Deskripsi belum tersedia.

Target Protein:
Glyceraldehyde-3-phosphate dehydrogenase
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