Hasil Pencarian (2)
small molecule | CAS: 1703748-89-3
In April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) as an alternative treatment opti…
Kategori:
Cytochrome P-450 CYP3A InhibitorsCytochrome P-450 CYP3A SubstratesCytochrome P-450 CYP3A4 Inhibitors
+6
Target Protein:
Substance-P receptor
Waktu ParuhNetupitant is elimi…
Vol. DistribusiThe mean SD volume …
KlirensNetupitant has a me…
Genetik
-
small molecule | CAS: 290297-26-6
Netupitant is an antiemitic drug approved by the FDA in October 2014 for use in combination with palonosetron for the prevention of acute and delayed vomiting and nausea associated with cancer chemotherapy including highly emetogenic chemotherapy. Netupitant …
Kategori:
AcetamidesAmidesBCRP/ABCG2 Inhibitors
+15
Target Protein:
Substance-P receptor
Waktu Paruh96 hours with CV% o…
Vol. DistribusiIn cancer patients,…
KlirensEstimated systemic …
Genetik
-