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Total database: 17430
Struktur (SMILES)
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Target
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Hasil Pencarian (2)

Lopinavir Approved DB01601
small molecule | CAS: 192725-17-0

Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection.[L11163] Lopinavir is marketed and administered exclusively in combination with [ritonavir] - this combination, first marketed…

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +42
Target Protein:
Pol polyprotein
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe estimated appar…
Genetik -
Nelfinavir Approved DB00220
small molecule | CAS: 159989-64-7

Nelfinavir is a potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. Nelfinavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, …

Kategori:
Anti-HIV AgentsAnti-Infective AgentsAnti-Retroviral Agents +45
Target Protein:
HIV-1 protease
Waktu ParuhThe terminal half-l…
Vol. DistribusiThe apparent volume…
KlirensOral clearance esti…
Genetik -