Hasil Filter

8

Total database: 17430
Struktur (SMILES)
8 (100.0%)
Target
5 (62.5%)
Genomik
1 (12.5%)
Referensi
8 (100.0%)

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Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (8)

Antrafenine Approved DB01419
small molecule | CAS: 55300-29-3

Antrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen. It is not widely used as it has largely been replaced by newer drugs.

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAnti-Inflammatory Agents +4
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
small molecule | CAS: 102580-74-5

Deskripsi belum tersedia.

Kategori:
AminesAnti-Infective AgentsAnti-Infective Agents, Local +5
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Giripladib DB15426
small molecule | CAS: 865200-20-0

Giripladib is under investigation in clinical trial NCT00396955 (A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee).

Kategori:
Acids, CarbocyclicAmidesBenzene Derivatives +3
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Nabumetone Approved DB00461
small molecule | CAS: 42924-53-8

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiti…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAnalgesics +21
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
Waktu Paruh6-MNA has a mean ha…
Vol. DistribusiThe Vd of 6-MNA rep…
Klirens6-MNA has an appare…
Genetik -
Naproxcinod DB06682
small molecule | CAS: 163133-43-5

Deskripsi belum tersedia.

Kategori:
Antiinflammatory and Antirheumatic ProductsAntiinflammatory and Antirheumatic Products, Non-SteroidsCardiovascular Agents +5
Target Protein:
Prostaglandin G/H synthase 1Prostaglandin G/H synthase 2
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Naproxen Approved DB00788
small molecule | CAS: 22204-53-1

Naproxen is classified as a nonsteroidal anti-inflammatory dug (NSAID) and was initially approved for prescription use in 1976 and then for over-the-counter (OTC) use in 1994.[A178975] It can effectively manage acute pain as well as pain related to rheumatic …

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAnalgesics +41
Target Protein:
Pancreatic triacylglycerol lipaseProstaglandin G/H synthase 1Prostaglandin G/H synthase 2 +1
Waktu ParuhThe elimination hal…
Vol. DistribusiNaproxen has a volu…
KlirensNaproxen is cleared…
Genetik -
small molecule | CAS: 385800-16-8

Naproxen etemesil has been used in trials studying the treatment of Osteoarthritis.

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Zolmitriptan Approved DB00315
small molecule | CAS: 139264-17-8

Zolmitriptan is a member of the triptan class of 5-hydroxytryptamine(5-HT)<sub>1B/1D/(1F)</sub> receptor agonists used to treat acute migraine.[A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilic…

Kategori:
Agents that produce hypertensionAminesAnalgesics +24
Target Protein:
5-hydroxytryptamine receptor 1B5-hydroxytryptamine receptor 1D5-hydroxytryptamine receptor 1F +5
Gen Terkait:
GNB3
Waktu ParuhZolmitriptan has a …
Vol. DistribusiZolmitriptan has a …
KlirensZolmitriptan has a …
Genetik 1 Varian