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Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
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Referensi
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Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Mycophenolate mofetil Approved DB00688
small molecule | CAS: 128794-94-5

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH).[A180805] This drug is an immunosuppressant combined with drugs such as [Cyclospor…

Kategori:
Agents Causing Muscle ToxicityAnti-Bacterial AgentsAnti-Infective Agents +23
Target Protein:
Prostaglandin E2 receptor EP2 subtypeInosine-5'-monophosphate dehydrogenase 1Inosine-5'-monophosphate dehydrogenase 2 +1
Waktu ParuhThe average apparen…
Vol. DistribusiThe volume of distr…
KlirensPlasma clearance of…
Genetik -
Mycophenolic acid Approved DB01024
small molecule | CAS: 24280-93-1

Mycophenolic acid is a potent immunosuppressant agent that inhibits _de novo_ purine biosynthesis.[L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal and antiviral properties.[A249170]. Mycophenolic acid is us…

Kategori:
Acids, AcyclicAnti-Bacterial AgentsAnti-Infective Agents +27
Target Protein:
Inosine-5'-monophosphate dehydrogenase 2Inosine-5'-monophosphate dehydrogenase 1
Waktu ParuhThe mean eliminatio…
Vol. DistribusiAt steady state, th…
KlirensThe mean clearance …
Genetik -
Voclosporin Approved DB11693
small molecule | CAS: 515814-01-4

Lupus nephritis (LN) is a type of glomerulonephritis occurring in patients with systemic lupus erythematosus (SLE). LN is a significant cause of renal failure, morbidity, and death in patients with SLE. Within 10 years of being diagnosed with SLE, 5-20% of …

Kategori:
Amino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating AgentsCalcineurin Inhibitor Immunosuppressant +16
Target Protein:
Guided entry of tail-anchored proteins factor CAMLGProtein phosphatase 3 catalytic subunit alphaCalcineurin subunit B type 1 +1
Waktu ParuhThe average termina…
Vol. DistribusiThe apparent volume…
KlirensThe mean apparent s…
Genetik -