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Total database: 17430
Struktur (SMILES)
5 (83.3%)
Target
4 (66.7%)
Genomik
0 (0%)
Referensi
6 (100.0%)

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Distribusi Wujud Zat

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Hasil Pencarian (6)

Efinopegdutide DB15077
biotech | CAS: 2055640-93-0

Efinopegdutide is under investigation in clinical trial NCT03606057 (A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy Adults: a Thorough ECG Study Employing Placebo, JNJ-64565…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
GSK-945237 DB15345
small molecule | CAS: 944406-54-6

GSK-945237 is under investigation in clinical trial NCT01039610 (A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and Repeat Escalating Oral Doses of GSK945237; the Effe…

Kategori:
Heterocyclic Compounds, Fused-Ring
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Levofloxacin Approved DB01137
small molecule | CAS: 100986-85-4

Levofloxacin is a fluoroquinolone antibiotic and the optical S-(-) isomer of racemic [ofloxacin].[A190663] It reportedly carries 8 to 128-fold more activity against both gram-negative and gram-positive bacteria compared to R-(+)-ofloxacin[A190663] and remains…

Kategori:
4-QuinolonesAlimentary Tract and MetabolismAnti-Bacterial Agents +35
Target Protein:
DNA gyrase subunit ADNA gyrase subunit BDNA gyrase subunit A +1
Waktu ParuhThe average termina…
Vol. DistribusiLevofloxacin is wid…
KlirensThe average apparen…
Genetik -
Moxifloxacin Approved DB00218
small molecule | CAS: 151096-09-2

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Kategori:
4-QuinolonesAnti-Bacterial AgentsAnti-Infective Agents +18
Target Protein:
DNA gyrase subunit ADNA gyrase subunit BDNA gyrase subunit A +3
Waktu Paruh11.5-15.6 hours (si…
Vol. Distribusi* 1.7 to 2.7 L/kg
Klirens* 12 +/- 2 L/hr
Genetik -
PF-00610355 DB11871
small molecule | CAS: 862541-45-5

PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.

Kategori:
AcetamidesAdrenergic AgonistsAdrenergic beta-2 Receptor Agonists +7
Target Protein:
Beta-2 adrenergic receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ritobegron DB12080
small molecule | CAS: 255734-04-4

Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin in Healthy Male and Female Volunteers).

Kategori:
Acids, AcyclicAdrenergic AgentsAdrenergic Agonists +15
Target Protein:
Beta-3 adrenergic receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -