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3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
0 (0%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Ketoconazole Approved DB01026
small molecule | CAS: 65277-42-1

Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity…

Kategori:
14-alpha Demethylase InhibitorsAgents causing hyperkalemiaAnti-Infective Agents +55
Target Protein:
Lanosterol 14-alpha demethylaseLanosterol 14-alpha demethylaseSteroid 17-alpha-hydroxylase/17,20 lyase +5
Waktu ParuhKetoconazole experi…
Vol. DistribusiKetoconazole has an…
KlirensKetoconazole has an…
Genetik -
Miconazole Approved DB01110
small molecule | CAS: 22916-47-8

Miconazole is a broad-spectrum azole antifungal with some activity against Gram-positive bacteria as well.[A203636] It is widely used to treat mucosal yeast infections, including both oral and vaginal infections; although intravenous miconazole is no longer a…

Kategori:
14-alpha Demethylase InhibitorsAnti-Infective AgentsAntifungal Agents +41
Target Protein:
Lanosterol 14-alpha demethylaseNitric oxide synthase 3Nitric oxide synthase, inducible +5
Waktu ParuhMiconazole has a te…
Vol. DistribusiA 1200 mg miconazol…
Klirens-
Genetik -
Pramiconazole DB06295
small molecule | CAS: 219923-85-0

Deskripsi belum tersedia.

Target Protein:
Lanosterol 14-alpha demethylase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -