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3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
0 (0%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Ibrexafungerp Approved DB12471
small molecule | CAS: 1207753-03-4

Ibrexafungerp, also known as SCY-078 or MK-3118, is a novel enfumafungin derivative oral triterpene antifungal approved for the treatment of vulvovaginal candidiasis (VVC), also known as a vaginal yeast infection.[A235384,L34349] It was developed out of a nee…

Kategori:
Anti-Infective AgentsAntifungal AgentsAntiinfectives for Systemic Use +17
Target Protein:
1,3-beta-glucan synthase component GSC2GTP-binding protein RHO1
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensClearance values of…
Genetik -
Micafungin Approved DB01141
small molecule | CAS: 235114-32-6

Micafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntifungal Agents +9
Target Protein:
1,3-beta-glucan synthase component FKS11,3-beta-glucan synthase component GSC2
Waktu Paruh14-17 hours
Vol. Distribusi* 0.39 ± 0.11 L/kg …
Klirens* 0.359 +/- 0.179 m…
Genetik -
Rezafungin Approved DB16310
small molecule | CAS: 1396640-59-7

Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as [caspofungin] and [micafungin], rezafungin has long?acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining hig…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsAntifungal Agents +8
Target Protein:
1,3-beta-glucan synthase component FKS11,3-beta-glucan synthase component GSC2
Waktu ParuhRezafungin has a te…
Vol. DistribusiRezafungin has a vo…
KlirensRezafungin has an e…
Genetik -