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Mevastatin DB06693

small molecule | CAS: 73573-88-3

Mevastatin or compactin is a cholesterol-lowering agent isolated from <i>Penicillium citinium</i>. It was the first discovered agent belonging to the class of cholesterol-lowering medications known as statins. During a search for antibiotic compounds produced…

Kategori:

Agents Causing Muscle ToxicityAnti-Infective AgentsAnticholesteremic Agents +7

Target Protein:

3-hydroxy-3-methylglutaryl-coenzyme A reductase

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Pravastatin Approved DB00175

small molecule | CAS: 81093-37-0

Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin].[T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug.[T274] This dr…

Kategori:

Agents Causing Muscle ToxicityAnticholesteremic AgentsBCRP/ABCG2 Inhibitors +20

Target Protein:

3-hydroxy-3-methylglutaryl-coenzyme A reductaseHistone deacetylase 2

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Hasil Pencarian (2)