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5

Total database: 17430
Struktur (SMILES)
5 (100.0%)
Target
3 (60.0%)
Genomik
0 (0%)
Referensi
5 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (5)

Avibactam Approved DB09060
small molecule | CAS: 1192500-31-4

Avibactam is a non-?-lactam ?-lactamase inhibitor that is available in combination with ceftazidime (Avycaz). This combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in combination with metroni…

Kategori:
Anti-Infective AgentsAza Compoundsbeta-Lactamase Inhibitors +2
Target Protein:
Beta-lactamase TEMBeta-lactamase CTX-MBeta-lactamase +7
Waktu ParuhCeftazidime-avibact…
Vol. DistribusiThe steady state vo…
KlirensAvibactam and cefta…
Genetik -
Bismuth subsalicylate Approved DB01294
small molecule | CAS: 14882-18-9

Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of [salicylic acid] linked to trivalent [bismuth cation]. Each molecule of bismuth subsalicylate…

Kategori:
Acids, CarbocyclicAntacids and AdsorbentsAntidiarrheals +16
Waktu ParuhThe terminal half-l…
Vol. DistribusiThere is no informa…
KlirensThe renal clearance…
Genetik -
Metronidazole Approved DB00916
small molecule | CAS: 443-48-1

Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics.[L3754] It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A18103…

Kategori:
Agents that reduce seizure thresholdAlimentary Tract and MetabolismAnti-Bacterial Agents +38
Target Protein:
Oxygen-insensitive NADPH nitroreductaseAnaerobic bacterial DNAProtozoal DNA
Waktu ParuhThe elimination hal…
Vol. DistribusiMetronidazole is wi…
KlirensDose adjustments ma…
Genetik -
small molecule | CAS: 13182-89-3

Deskripsi belum tersedia.

Kategori:
ImidazolesNitro CompoundsNitroimidazoles
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Pantoprazole Approved DB00213
small molecule | CAS: 102625-70-7

Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatmen…

Kategori:
2-PyridinylmethylsulfinylbenzimidazolesAcid ReducersAlimentary Tract and Metabolism +27
Target Protein:
Potassium-transporting ATPase alpha chain 1Potassium-transporting ATPase subunit betaN(G),N(G)-dimethylarginine dimethylaminohydrolase 1
Waktu ParuhAbout 1 hour[F3202]
Vol. DistribusiThe apparent volume…
Klirens**Adults**: With in…
Genetik -