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3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
0 (0%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Balsalazide Approved DB01014
small molecule | CAS: 80573-04-2

Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease. It is sold under the name "Colazal" in the US and "Colazide" in the UK. The chemical name is (E)-5-[[-4-(2-carboxyethyl) aminocarbonyl] phenyl]azo] -2-hydroxybenz…

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +27
Target Protein:
Peroxisome proliferator-activated receptor gammaProstaglandin G/H synthase 2Prostaglandin G/H synthase 1 +1
Waktu ParuhHalf-life could not…
Vol. Distribusi-
Klirens-
Genetik -
Mesalazine Approved DB00244
small molecule | CAS: 89-57-6

An anti-inflammatory agent, structurally related to the salicylates and non-steroidal anti-inflammatory drugs like acetylsalicylic acid, which is active in inflammatory bowel disease [A174022]. Although demonstrably effective in treating and maintaining remis…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAminosalicylate +13
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1Polyunsaturated fatty acid 5-lipoxygenase +4
Waktu ParuhFor the delayed-rel…
Vol. DistribusiFor the extended-re…
KlirensThe mean (SD) renal…
Genetik -
Sulfasalazine Approved DB00795
small molecule | CAS: 599-79-1

Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA).[L39065, A255582] Metab…

Kategori:
Agents causing hyperkalemiaAgents that produce hypertensionAlimentary Tract and Metabolism +23
Target Protein:
Broad substrate specificity ATP-binding cassette transporter ABCG2Transcription factor RelBTranscription factor p65 +12
Waktu ParuhThe observed plasma…
Vol. DistribusiFollowing intraveno…
KlirensThe calculated clea…
Genetik -