Hasil Filter

11

Total database: 17430
Struktur (SMILES)
11 (100.0%)
Target
6 (54.5%)
Genomik
1 (9.1%)
Referensi
11 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (11)

small molecule | CAS: 64-52-8

1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. It is sold as a "synthetic heroin."

Kategori:
Cytochrome P-450 CYP2D6 InhibitorsCytochrome P-450 CYP2D6 Inhibitors (strength unknown)Cytochrome P-450 Enzyme Inhibitors
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Alphameprodine DB01499
small molecule | CAS: 468-51-9

Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred…

Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Anileridine Approved DB00913
small molecule | CAS: 144-14-9

Anileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain. Narcotic analgesics act in the central nervous system (CNS) to relieve pain. Some of their side effects are also caused by…

Kategori:
AnestheticsAnesthetics, GeneralNervous System +2
Target Protein:
Mu-type opioid receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Betameprodine DB01552
small molecule | CAS: 468-50-8

Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine).…

Waktu Paruh-
Vol. Distribusi-
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Genetik -
Betaprodine DB01473
small molecule | CAS: 468-59-7

An opioid analgesic chemically related to and with an action resembling that of meperidine, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures.…

Waktu Paruh-
Vol. Distribusi-
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Genetik -
small molecule | CAS: 13147-09-6

Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine. It has been listed as a Schedule I controlled drug in the United States, and thus is not used clinically. It is known to be a designer drug, synthesized in 1977…

Kategori:
Isonipecotic AcidsPiperidines
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Difenoxin Approved DB01501
small molecule | CAS: 28782-42-5

Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. However, it is listed as a Schedule IV controlled drug if combined with atropine, w…

Kategori:
Alimentary Tract and MetabolismAntidiarrhealsAntidiarrheals, Intestinal Antiinflammatory/antiinfective Agents +4
Target Protein:
Mu-type opioid receptor
Waktu ParuhThe elimination hal…
Vol. Distribusi-
Klirens-
Genetik -
Diphenoxylate Approved DB01081
small molecule | CAS: 915-30-0

A meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. Its unesterified metabolite difenoxin has similar properties and is used similarly. It has little or no analgesic activity. This medica…

Kategori:
Alimentary Tract and MetabolismAnalgesicsAntidiarrheals +11
Target Protein:
Mu-type opioid receptorDelta-type opioid receptor
Waktu Paruh12-14 hours
Vol. Distribusi-
Klirens-
Genetik -
Ketorolac Approved DB00465
small molecule | CAS: 74103-06-3

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.[L6358][L6508][L11055][L3674][L11070] It's analgesic properties make it a useful pain manage…

Kategori:
Acetic Acid Derivatives and Related SubstancesAgents causing hyperkalemiaAgents that produce hypertension +26
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
Waktu ParuhKetorolac trometham…
Vol. DistribusiThe apparent volume…
KlirensThe plasma clearanc…
Genetik -
Meperidine Approved DB00454
small molecule | CAS: 57-42-1

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with mor…

Kategori:
AdjuvantsAdjuvants, AnesthesiaAgents that reduce seizure threshold +34
Target Protein:
Kappa-type opioid receptorGlutamate receptor ionotropic, NMDA 1Glutamate receptor ionotropic, NMDA 2B +9
Waktu ParuhInitial distributio…
Vol. DistribusiMeperidine crosses …
Klirens-
Genetik -
Morphine Approved DB00295
small molecule | CAS: 57-27-2

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.[A176050] Morphine is still routinely used today, though there …

Kategori:
AlkaloidsAnalgesicsAnesthetics +25
Target Protein:
Mu-type opioid receptorKappa-type opioid receptorDelta-type opioid receptor +1
Gen Terkait:
ABCB1 OPRM1
Waktu ParuhMorphine has a half…
Vol. DistribusiThe volume of distr…
KlirensThe apparent cleara…
Genetik 2 Varian