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2

Total database: 17430
Struktur (SMILES)
2 (100.0%)
Target
2 (100.0%)
Genomik
0 (0%)
Referensi
2 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (2)

Diclofenac Approved DB00586
small molecule | CAS: 15307-86-5

Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain sign…

Kategori:
Acetic Acid Derivatives and Related SubstancesAcids, CarbocyclicAgents causing angioedema +58
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
Waktu ParuhThe terminal half-l…
Vol. DistribusiDiclofenac has a to…
KlirensDiclofenac has a pl…
Genetik -
Mefenamic acid Approved DB00784
small molecule | CAS: 61-68-7

A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.

Kategori:
Acids, CarbocyclicAgents causing hyperkalemiaAgents that produce hypertension +37
Target Protein:
Prostaglandin G/H synthase 2Prostaglandin G/H synthase 1
Waktu Paruh2 hours
Vol. Distribusi* 1.06 L/kg [Normal…
Klirens* Oral cl=21.23 L/h…
Genetik -