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Total database: 17430
Struktur (SMILES)
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Target
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Hasil Pencarian (5)

Levonorgestrel Approved DB00367
small molecule | CAS: 797-63-7

Levonorgestrel (LNG) is a synthetic progestogen similar to [Progesterone] used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an …

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +23
Target Protein:
Progesterone receptor3-oxo-5-alpha-steroid 4-dehydrogenase 1Estrogen receptor +3
Waktu ParuhThe elimination hal…
Vol. DistribusiOne pharmacokinetic…
KlirensClearance was found…
Genetik -
Norelgestromin Approved DB06713
small molecule | CAS: 53016-31-2

Norelgestromin is a drug used in contraception. Norelgestromin is the active progestin responsible for the progestational activity that occurs in women after application of ORTHO EVRA patch.

Kategori:
Adrenal Cortex HormonesAminesCombination Contraceptives (with Estrogen and derivatives) +17
Target Protein:
Progesterone receptorAlbuminAndrogen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Norethisterone Approved DB00717
small molecule | CAS: 68-22-4

Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins.[A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its derivati…

Kategori:
Adrenal Cortex HormonesAnti-Gonadotropin-Releasing HormonesCombination Contraceptives (with Estrogen and derivatives) +34
Target Protein:
Progesterone receptorAndrogen receptorGlucocorticoid receptor
Waktu ParuhThe half-life of no…
Vol. DistribusiThe volume of distr…
KlirensThe plasma clearanc…
Genetik -
Norgestrel Approved DB09389
small molecule | CAS: 6533-00-2

Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only the levorotary enantio…

Kategori:
Adrenal Cortex HormonesCombination Contraceptives (with Estrogen and derivatives)Contraceptive Agents, Female +20
Target Protein:
Progesterone receptor3-oxo-5-alpha-steroid 4-dehydrogenase 1Androgen receptor
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Ulipristal Approved DB08867
small molecule | CAS: 159811-51-5

Ulipristal is a selective progesterone receptor modulator used for the purposes of emergency contraception (Ella) and for the treatment of uterine fibroids (Fibristal). It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist ac…

Kategori:
Adrenal Cortex HormonesContraceptive Agents, FemaleContraceptive Agents, Hormonal +16
Target Protein:
Progesterone receptorGlucocorticoid receptorAndrogen receptor
Waktu ParuhMean elimination ha…
Vol. Distribusi-
KlirensMean oral clearance…
Genetik -