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3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
0 (0%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Isosorbide Approved DB09401
small molecule | CAS: 652-67-5

Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. Currently, isosorbide is an organic nitrate currently available in the [isosorbide monon…

Kategori:
AlcoholsAntianginal AgentsCarbohydrates +8
Target Protein:
Guanylate cyclase
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Isosorbide dinitrate Approved DB00883
small molecule | CAS: 87-33-2

A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.

Kategori:
Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseAlcoholsAntianginal Agents +17
Target Protein:
Atrial natriuretic peptide receptor 1
Waktu Paruh1 hour
Vol. Distribusi* 2 to 4 L/kg
Klirens-
Genetik -
Isosorbide mononitrate Approved DB01020
small molecule | CAS: 16051-77-7

Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.[L11698, L11743] Isosorbide mono…

Kategori:
AlcoholsAntianginal AgentsCarbohydrates +14
Target Protein:
Guanylate cyclase soluble subunit alpha-2
Waktu ParuhThe elimination hal…
Vol. DistribusiThe volume of distr…
KlirensThe total body clea…
Genetik -