Hasil Filter

4

Total database: 17430
Struktur (SMILES)
1 (25.0%)
Target
4 (100.0%)
Genomik
0 (0%)
Referensi
4 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (4)

Interferon beta-1a Approved DB00060
biotech | CAS: 145258-61-3

Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interfe…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAnti-Infective Agents +16
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu Paruh10 hrs
Vol. Distribusi-
Klirens* 33-55 L/hour [Hea…
Genetik -
Ocrelizumab Approved DB11988
biotech | CAS: 637334-45-3

Ocrelizumab is a CD20-directed cytolytic antibody indicated for the treatment of patients with primary progressive or relapsing forms of multiple sclerosis (MS).[L42895] It is a second-generation recombinant humanized monoclonal IgG1 antibody that selectively…

Kategori:
Amino Acids, Peptides, and ProteinsAntibodiesAntibodies, Monoclonal +14
Target Protein:
B-lymphocyte antigen CD20
Waktu ParuhThe terminal elimin…
Vol. DistribusiIn a population pha…
KlirensThe constant cleara…
Genetik -
Ozanimod Approved DB12612
small molecule | CAS: 1306760-87-1

Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) [L11025] and was approved by the FDA …

Kategori:
Antineoplastic and Immunomodulating AgentsBCRP/ABCG2 SubstratesCytochrome P-450 CYP2C8 Substrates +13
Target Protein:
Sphingosine 1-phosphate receptor 1Sphingosine 1-phosphate receptor 5
Waktu ParuhThe half-life of oz…
Vol. DistribusiThe average volume …
KlirensThe mean apparent o…
Genetik -
Peginterferon beta-1a Approved DB09122
biotech | CAS: 1211327-92-2

Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +13
Target Protein:
Interferon alpha/beta receptor 1
Waktu ParuhThe mean half life …
Vol. DistribusiThe volume of distr…
KlirensThe average steady …
Genetik -