Hasil Pencarian (2)
small molecule | CAS: 1217486-61-7
Alpelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potent antitumor activity. It works by selectively inhibiting class I PI3K p110? [A179203], which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological proce…
Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Inhibitors
+32
Target Protein:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Waktu ParuhThe mean half life …
Vol. DistribusiThe apparent volume…
KlirensThe mean apparent o…
Genetik
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small molecule | CAS: 870281-82-6
Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is…
Kategori:
Antineoplastic AgentsAntineoplastic and Immunomodulating AgentsBCRP/ABCG2 Substrates
+47
Target Protein:
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
Waktu ParuhThe terminal elimin…
Vol. Distribusi23 L
Klirens14.9 L/hr
Genetik
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