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Total database: 17430
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Hasil Pencarian (5)

Glatiramer Approved DB05259
biotech | CAS: 28704-27-0

Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively.[L41940] Since glatiramer acetate is a heterogeneous drug, th…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +5
Target Protein:
MHC class II protein complex
Waktu ParuhNot available.
Vol. DistribusiNot available.
KlirensNot available.
Genetik -
Human interferon beta Approved DB14999
biotech | CAS: 74899-71-1

Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992.[L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and s…

Kategori:
Amino Acids, Peptides, and ProteinsAnti-Infective AgentsBiological Factors +7
Target Protein:
Interferon alpha/beta receptor 1
Waktu ParuhThe mean terminal e…
Vol. DistribusiThe average state v…
KlirensAverage serum clear…
Genetik -
biotech

Human interleukin-6 is under investigation in clinical trial NCT03170245 (Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients).

Kategori:
Amino Acids, Peptides, and ProteinsBiological FactorsCytokines +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -
Interferon beta-1a Approved DB00060
biotech | CAS: 145258-61-3

Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interfe…

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAnti-Infective Agents +16
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu Paruh10 hrs
Vol. Distribusi-
Klirens* 33-55 L/hour [Hea…
Genetik -
Interferon beta-1b Approved DB00068
biotech | CAS: 145155-23-3

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD

Kategori:
Adjuvants, ImmunologicAmino Acids, Peptides, and ProteinsAntineoplastic and Immunomodulating Agents +15
Target Protein:
Interferon alpha/beta receptor 1Interferon alpha/beta receptor 2
Waktu Paruh-
Vol. Distribusi* 0.25 to 2,88 L/kg
Klirens* 9.4 – 28.9 mL/min…
Genetik -