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Total database: 17430
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Hasil Pencarian (3)

Elbasvir Approved DB11574
small molecule | CAS: 1370468-36-2

Elbasvir is a direct-acting antiviral medication used as part of combination therapy to treat chronic hepatitis C, an infectious liver disease caused by infection with hepatitis C virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine d…

Kategori:
Antiinfectives for Systemic UseAntiviral AgentsAntivirals for Systemic Use +18
Target Protein:
Nonstructural protein 5A
Waktu ParuhThe geometric mean …
Vol. DistribusiElbasvir has an est…
KlirensThe clearance of el…
Genetik -
Grazoprevir Approved DB11575
small molecule | CAS: 1350514-68-9

Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nin…

Kategori:
Acids, AcyclicAmidesAnti-Infective Agents +24
Target Protein:
Genome polyprotein
Waktu ParuhThe geometric mean …
Vol. DistribusiGrazoprevir has an …
KlirensThe clearance of Gr…
Genetik -
Uprifosbuvir DB15206
small molecule | CAS: 1496551-77-9

Uprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and GT2 Infection (MK-3682-011)).

Kategori:
Anti-Infective AgentsAntiviral AgentsNucleic Acids, Nucleotides, and Nucleosides +4
Waktu Paruh-
Vol. Distribusi-
Klirens-
Genetik -