Hasil Filter

3

Total database: 17430
Struktur (SMILES)
3 (100.0%)
Target
3 (100.0%)
Genomik
1 (33.3%)
Referensi
3 (100.0%)

Tipe Molekul

Distribusi Wujud Zat

Status Regulasi

Hasil Pencarian (3)

Fenofibrate Approved DB01039
small molecule | CAS: 49562-28-9

Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 Decemb…

Kategori:
Acids, AcyclicAgents Causing Muscle ToxicityBenzene Derivatives +39
Target Protein:
Peroxisome proliferator-activated receptor alphaNuclear receptor subfamily 1 group I member 2Matrix metalloproteinase-25
Waktu ParuhFenofibric acid, th…
Vol. DistribusiThe volume of distr…
KlirensThe oral clearance …
Genetik -
Gemfibrozil Approved DB01241
small molecule | CAS: 25812-30-0

Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias.[A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exer…

Kategori:
Acids, AcyclicAgents Causing Muscle ToxicityBenzene Derivatives +53
Target Protein:
Peroxisome proliferator-activated receptor alphaLipoprotein lipaseSolute carrier organic anion transporter family member 1B1 +3
Waktu ParuhGemfibrozil has a p…
Vol. DistribusiThe volume of distr…
KlirensThe clearance of ge…
Genetik -
Rosuvastatin Approved DB01098
small molecule | CAS: 287714-41-4

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous prod…

Kategori:
Agents Causing Muscle ToxicityAlimentary Tract and MetabolismAmides +32
Target Protein:
3-hydroxy-3-methylglutaryl-coenzyme A reductaseIntegrin alpha-L
Gen Terkait:
KIF6 HMGCR ABCG2
Waktu ParuhThe elimination hal…
Vol. DistribusiRosuvastatin underg…
Klirens-
Genetik 3 Varian